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Home > WI Providers > Neurologists

Dr. Diane S. Book, MD

Accepting New Patients

(59 Ratings)

Specializes in: Neurology (Brain & Spinal Cord Disease)

Medical College of Wisconsin (1991)

Professional interests include: memory disorders, stroke, ischemic stroke, and more.

900 N 92nd Street
Milwaukee, WI 53226

(414) 805-5400

Dr. Diane S. Book, MD is a neurologist in Milwaukee, WI specializing in neurology (brain & spinal cord disease). She graduated from Medical College of Wisconsin in 1991 and has 35 years of experience. Dr. Diane S. Book, MD is affiliated with Medical College of Wisconsin, Froedtert Hospital, Froedtert & the Medical College of Wisconsin Regional Health Network and Froedtert Hospital - Milwaukee.

Office Locations

900 N 92nd Street
Milwaukee, WI 53226

(414) 805-5400

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Some issues Dr. Diane S. Book, MD can help you with:

Ischemic Stroke

Ischemic stroke is the more common form of stroke and occurs when a blood vessel in the brain becomes blocked. Ischemic strokes are caused by blood clots or by built-up plaque (deposits of fat and cholesterol) in the arteries and are dangerous medical events that require immediate treatment.

Ischemic strokes are severe because it restricts blood flow and an inadequate blood supply damages the brain, which cannot function without a steady supply of oxygen and nutrients. Ischemic strokes may alter appearance by leaving one side of the face paralyzed, also affecting speech and communication. Additionally, ischemic strokes can result in impaired movement, cognitive ability, and can impede important physical functions like walking.

The main cause of ischemic stroke is from plaque (deposits of fat and cholesterol) accumulating in blood vessels. Plaque causes atherosclerosis, a condition where the blood vessels narrow and harden with cholesterol, fat, and calcium, causing damage to the endothelium (inner layer of cells in the arteries), which in turn restricts blood flow. At some point, a large blockage of plaque or bits of broken up plaque may result in an ischemic stroke.

People who are older are more likely to have ischemic strokes due to accumulated plaque. Additionally, certain repeated behaviors are associated with an increased risk of ischemic stroke. These behaviors include:

Smoking
High fat diet
Lack of exercise
High salt diet
Alcohol abuse

Conditions such as heart disease, diabetes, high blood pressure, and high levels of cholesterol and lipids are also known to be correlated with ischemic strokes. If possible, people are advised to avoid modifiable risk factors (factors one can change themselves) such as smoking and lack of exercise by keeping an active lifestyle and a healthy diet.

Signs of stroke include:

Disorientation or confusion
Difficulty speaking
Difficulty walking
Impaired vision
Weakness in the face, legs, or arms
Severe headaches

When someone suspected of having a stroke reaches the hospital, the patient will usually receive a CT or other scan that provides an image of the brain. The scan results can reveal clotted or leaking blood in the brain. Physical exams, neurological exams, and blood tests may also be used to check for blood clotting and sugar. Hospital treatment generally begins immediately if a stroke is detected.

Medical treatment for ischemic strokes includes a thrombolytic medicine which breaks up and disperses blood clots. This medicine can greatly improve stroke recovery and long-term health. However, the thrombolytic medicine must be administered as soon as possible to achieve these results. Other treatments for ischemic strokes are blood thinners and thrombectomy, a surgical procedure to remove a blood clot in the brain. Thrombectomy is performed using a catheter (thin needle) to the artery to reach the blood clot and mechanically remove it. With the clot removed, normal blood flow to the brain resumes. Thrombectomy is typically performed at most six hours after a patient shows signs of a stroke.

Ischemic stroke patients who have lost some essential functions while the blood flow to their brain was obstructed may receive post-stroke rehabilitation to rebuild their physical and mental abilities. Some restorative treatments include occupational, physical, and speech therapy. Patients may also receive care from neurologists, who can assist patients in recovering certain brain functions and cognitive abilities, and rehabilitation psychologists, who may help patients with their emotional, behavioral, and cognitive recovery. Some stroke patients require lengthy rehabilitation and may never fully regain function, while others may recover more quickly. While the fastest recovery improvements are usually seen in the first three or four months, ischemic stroke rehabilitation can last for years.

If someone begins to show signs of ischemic stroke, contact emergency services and call 9-1-1 immediately since blood flow must be restored as soon as possible to avoid significant brain damage. If an ambulance takes the person to the hospital, paramedics can initiate ischemic stroke treatment as soon as the patient enters the ambulance, allowing for more prompt medical intervention and care.

Stroke

A stroke is a medical emergency that occurs when a blood vessel supplying oxygen and nutrients to the brain is ruptured or blocked. The brain cannot function without a steady supply of oxygen and nutrients, so when the blood supply to the brain is interrupted, even for a brief moment, brain cells begin to die. When a sufficient number of brain cells die, the brain itself can no longer function, meaning that strokes are very dangerous. Strokes can result in impaired movement, speech, cognitive ability, the impairment of important physical functions, and even death.

Anyone can have a stroke, regardless of age and health. Strokes are known to happen at random. However, certain conditions and behaviors can increase one's risk of stroke over time.

Risk factors for stroke include:

Heart disease
Older age
Smoking
Diabetes
High blood pressure
High blood cholesterol and lipids

There are two main types of stroke: ischemic stroke and hemorrhagic stroke. Ischemic stroke occurs more commonly and is when a blood vessel in the brain becomes blocked. Blockages are caused by blood clots and built-up plaque (deposits of fat and cholesterol), which leads to atherosclerosis, a condition where the blood vessels narrow and harden. The resultant restricted blood flow may lead to an ischemic stroke by blocking essential oxygen to the brain, causing the heart to exert more effort to pump blood.

Hemorrhagic stroke occurs when a blood vessel in or around the brain ruptures. The burst vessel leaks blood into surrounding brain tissue, causing irreparable brain damage.

Hemorrhagic strokes are less common and may occur from head injuries, brain aneurysms, brain tumors, and bleeding disorders, amongst other conditions.

Both ischemic and hemorrhagic strokes require immediate medical treatment. Medical intervention can prevent severe and life-threatening brain damage. Signs of stroke include:

-Disorientation or confusion

-Difficulty speaking

-Difficulty walking

-Impaired vision

-Weakness in the face, legs, or arms

-Severe headaches

When someone suspected of having a stroke reaches the hospital, the patient will usually receive a CT or other scan that provides an image of the brain. The scan results can reveal clotted or leaking blood in the brain. Physical exams, neurological exams, and blood tests may also be used to check for blood clotting and sugar. Treatment begins generally immediately if a stroke is detected.

Medical treatment for ischemic strokes includes a thrombolytic medicine which breaks up and disperses blood clots. This medicine can greatly improve stroke recovery and long-term health. However, the thrombolytic medicine must be administered as soon as possible to achieve these results. Other treatments for ischemic strokes are blood thinners and thrombectomy, a surgical procedure to remove a blood clot in the brain. Thrombectomy is performed by inserting a catheter (thin needle) into the artery to reach the blood clot and mechanically remove it. With the clot removed, normal blood flow to the brain resumes. Thrombectomy is typically performed at most six hours after a patient shows signs of a stroke.

Hemorrhagic strokes are treated with blood-saving medication and surgery. For a hemorrhagic stroke caused by the rupture of an aneurysm (blood vessel bulges), surgery to stem the bleeding aneurysm and vessel may be used. One surgical technique is stent-assisted coiling, which adds a stent (small wire-meshed tube) into the blood vessel to block the leaking opening of the aneurysm. A non-surgical procedure is endovascular coiling, where a catheter (thin, hollow needle) places a platinum wire coil at the spot of the aneurysm. The coil blocks bleeding and prevents the aneurysm from continuing to leak blood. These procedures are usually combined with blood-thickening medications. Blood transfusions may be administered if substantial blood loss has occurred.

Since stroke patients may have lost some essential functions while the blood flow to their brains was obstructed, both ischemic stroke and hemorrhage stroke patients may receive post-stroke rehabilitation to rebuild their physical and mental abilities. Some restorative treatments include occupational, physical, and speech therapy. Patients may also receive care from neurologists, who can assist patients in recovering certain brain functions and cognitive abilities, and rehabilitation psychologists, who may help patients with their emotional, behavioral, and cognitive recovery. Some stroke patients require lengthy rehabilitation and may never fully regain function, while others may recover more quickly. While the fastest recovery improvements are usually seen in the first three or four months, stroke rehabilitation can last for years.

If someone begins to show signs of stroke, contact emergency services and call 9-1-1 immediately since blood flow must be restored as soon as possible to help avoid significant brain damage. If an ambulance takes the person to the hospital, paramedics can initiate stroke treatment as soon as the patient enters the ambulance, allowing for more prompt medical intervention and care.

In The News

“"The whole culture of treating stroke hasn't caught up with the science," said Diane Book, MD, medical director of the stroke program at Froedtert Hospital where Sam Denny now is undergoing...”—"Certified stroke centers and ischemic stroke treatment realities", KevinMD, July 2010

Medicare Procedure and Patient Information

2012 Medicare Procedure Volume

The top procedures that Dr. Diane S. Book, MD treated as a neurologist in Milwaukee, WI during 2012 were hospital care and inpatient care.

Volume of procedures performed by Dr. Diane S. Book, MD for Medicare patients.

doctor visit	211
hospital care	124
inpatient care	124

Medicare Procedure and Patient Information

2013 Medicare Procedure Volume

The top procedures that Dr. Diane S. Book, MD treated as a neurologist in Milwaukee, WI during 2013 were hospital care and inpatient care.

Volume of procedures performed by Dr. Diane S. Book, MD for Medicare patients.

doctor visit	272
hospital care	87
inpatient care	87

2013 Medicare Patient Data

Information about Medicare patients treated by Dr. Diane S. Book, MD.

**Gender**
Male	112
Female	149

**Ethnicity**
Non-Hispanic White	219
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	85
From 75 to 84	96
85 and over	43
Less than 65	37

Conditions of Medicare patients treated by Dr. Diane S. Book, MD in 2013

Hypertension	67
High Cholesterol	57
Stroke	43
Ischemic Heart Disease	38
Depression	34
Chronic Kidney Disease	23
Asthma	8
Osteoperosis	9
Atrial Fibrilation	15
Heart Failure	25
Chronic Obstructive Pulmonary Disease	10
Diabetes	30
Dementia	54
Cancer	10

Medicare Procedure and Patient Information

2014 Medicare Procedure Volume

The top procedures that Dr. Diane S. Book, MD treated as a neurologist in Milwaukee, WI during 2014 were hospital care and inpatient care.

Volume of procedures performed by Dr. Diane S. Book, MD for Medicare patients.

doctor visit	319
hospital care	169
inpatient care	169

2014 Medicare Patient Data

Information about Medicare patients treated by Dr. Diane S. Book, MD.

**Gender**
Male	158
Female	211

**Ethnicity**
Non-Hispanic White	284
Black	62
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	125
From 75 to 84	118
85 and over	63
Less than 65	63

Conditions of Medicare patients treated by Dr. Diane S. Book, MD in 2014

Hypertension	75
High Cholesterol	64
Stroke	46
Ischemic Heart Disease	42
Depression	32
Chronic Kidney Disease	31
Asthma	10
Osteoperosis	9
Atrial Fibrilation	20
Heart Failure	29
Chronic Obstructive Pulmonary Disease	12
Diabetes	29
Dementia	43
Cancer	12

Medicare Procedure and Patient Information

2015 Medicare Procedure Volume

The top procedures that Dr. Diane S. Book, MD treated as a neurologist in Milwaukee, WI during 2015 were hospital care, inpatient care and outpatient care.

Volume of procedures performed by Dr. Diane S. Book, MD for Medicare patients.

doctor visit	240
hospital care	156
inpatient care	145
outpatient care	11

2015 Medicare Patient Data

Information about Medicare patients treated by Dr. Diane S. Book, MD.

**Gender**
Male	274
Female	322

**Ethnicity**
Non-Hispanic White	484
Black	74
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	182
From 75 to 84	204
85 and over	110
Less than 65	100

Conditions of Medicare patients treated by Dr. Diane S. Book, MD in 2015

Hypertension	74
High Cholesterol	62
Stroke	46
Ischemic Heart Disease	40
Depression	32
Chronic Kidney Disease	38
Asthma	14
Osteoperosis	11
Atrial Fibrilation	15
Heart Failure	23
Chronic Obstructive Pulmonary Disease	13
Diabetes	34
Dementia	48
Cancer	12

Medicare Procedure and Patient Information

2016 Medicare Procedure Volume

The top procedures that Dr. Diane S. Book, MD treated as a neurologist in Milwaukee, WI during 2016 were hospital care and inpatient care.

Volume of procedures performed by Dr. Diane S. Book, MD for Medicare patients.

doctor visit	219
hospital care	231
inpatient care	231

2016 Medicare Patient Data

Information about Medicare patients treated by Dr. Diane S. Book, MD.

**Gender**
Male	127
Female	186

**Ethnicity**
Non-Hispanic White	239
Black	49
Hispanic	0
Asian	0
Other	11
Native American	0

**Age**
From 65 to 74	99
From 75 to 84	87
85 and over	63
Less than 65	64

Conditions of Medicare patients treated by Dr. Diane S. Book, MD in 2016

Hypertension	74
High Cholesterol	59
Stroke	42
Ischemic Heart Disease	39
Depression	41
Chronic Kidney Disease	39
Asthma	16
Osteoperosis	13
Atrial Fibrilation	16
Heart Failure	21
Chronic Obstructive Pulmonary Disease	12
Diabetes	31
Dementia	53
Cancer	12

Medicare Procedure and Patient Information

2017 Medicare Procedure Volume

The top procedures that Dr. Diane S. Book, MD treated as a neurologist in Milwaukee, WI during 2017 were hospital care and inpatient care.

Volume of procedures performed by Dr. Diane S. Book, MD for Medicare patients.

doctor visit	182
hospital care	237
inpatient care	237

2017 Medicare Patient Data

Information about Medicare patients treated by Dr. Diane S. Book, MD.

**Gender**
Male	129
Female	171

**Ethnicity**
Non-Hispanic White	236
Black	44
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	119
From 75 to 84	86
85 and over	57
Less than 65	38

Conditions of Medicare patients treated by Dr. Diane S. Book, MD in 2017

Hypertension	75
High Cholesterol	63
Stroke	45
Ischemic Heart Disease	38
Depression	41
Chronic Kidney Disease	42
Asthma	10
Osteoperosis	13
Atrial Fibrilation	17
Heart Failure	25
Chronic Obstructive Pulmonary Disease	15
Diabetes	27
Dementia	52
Cancer	15

Medicare Procedure and Patient Information

2018 Medicare Procedure Volume

The top procedures that Dr. Diane S. Book, MD treated as a neurologist in Milwaukee, WI during 2018 were hospital care and inpatient care.

Volume of procedures performed by Dr. Diane S. Book, MD for Medicare patients.

doctor visit	209
hospital care	182
inpatient care	182

2018 Medicare Patient Data

Information about Medicare patients treated by Dr. Diane S. Book, MD.

**Gender**
Male	133
Female	171

**Ethnicity**
Non-Hispanic White	238
Black	43
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	117
From 75 to 84	107
85 and over	48
Less than 65	32

Conditions of Medicare patients treated by Dr. Diane S. Book, MD in 2018

Hypertension	75
High Cholesterol	66
Stroke	52
Ischemic Heart Disease	44
Depression	40
Chronic Kidney Disease	45
Asthma	6
Osteoperosis	12
Atrial Fibrilation	19
Heart Failure	27
Chronic Obstructive Pulmonary Disease	16
Diabetes	32
Dementia	48
Cancer	15

Medicare Procedure and Patient Information

2019 Medicare Procedure Volume

The top procedures that Dr. Diane S. Book, MD treated as a neurologist in Milwaukee, WI during 2019 were hospital care and inpatient care.

Volume of procedures performed by Dr. Diane S. Book, MD for Medicare patients.

doctor visit	170
hospital care	250
inpatient care	250

2019 Medicare Patient Data

Information about Medicare patients treated by Dr. Diane S. Book, MD.

**Gender**
Male	111
Female	157

**Ethnicity**
Non-Hispanic White	202
Black	45
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	85
From 75 to 84	108
85 and over	41
Less than 65	34

Conditions of Medicare patients treated by Dr. Diane S. Book, MD in 2019

Hypertension	74
High Cholesterol	64
Stroke	47
Ischemic Heart Disease	38
Depression	39
Chronic Kidney Disease	40
Asthma	10
Osteoperosis	11
Atrial Fibrilation	18
Heart Failure	23
Chronic Obstructive Pulmonary Disease	12
Diabetes	31
Dementia	43
Cancer	12

Medicare Procedure and Patient Information

2020 Medicare Procedure Volume

The top procedures that Dr. Diane S. Book, MD treated as a neurologist in Milwaukee, WI during 2020 were hospital care and inpatient care.

Volume of procedures performed by Dr. Diane S. Book, MD for Medicare patients.

doctor visit	117
hospital care	148
inpatient care	148

2020 Medicare Patient Data

Information about Medicare patients treated by Dr. Diane S. Book, MD.

**Gender**
Male	97
Female	117

**Ethnicity**
Non-Hispanic White	166
Black	37
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	88
From 75 to 84	60
85 and over	30
Less than 65	36

Conditions of Medicare patients treated by Dr. Diane S. Book, MD in 2020

Hypertension	75
High Cholesterol	66
Stroke	50
Ischemic Heart Disease	37
Depression	36
Chronic Kidney Disease	39
Asthma	8
Osteoperosis	11
Atrial Fibrilation	14
Heart Failure	24
Chronic Obstructive Pulmonary Disease	10
Diabetes	29
Dementia	38
Cancer	10

Medicare Procedure and Patient Information

2021 Medicare Procedure Volume

The top procedures that Dr. Diane S. Book, MD treated as a neurologist in Milwaukee, WI during 2021 were hospital care and inpatient care.

Volume of procedures performed by Dr. Diane S. Book, MD for Medicare patients.

doctor visit	145
hospital care	249
inpatient care	249

2021 Medicare Patient Data

Information about Medicare patients treated by Dr. Diane S. Book, MD.

**Gender**
Male	117
Female	147

**Ethnicity**
Non-Hispanic White	214
Black	28
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	87
From 75 to 84	105
85 and over	41
Less than 65	31

Conditions of Medicare patients treated by Dr. Diane S. Book, MD in 2021

Hypertension	75
High Cholesterol	71
Stroke	55
Ischemic Heart Disease	41
Depression	34
Chronic Kidney Disease	42
Asthma	8
Osteoperosis	12
Atrial Fibrilation	18
Heart Failure	27
Chronic Obstructive Pulmonary Disease	13
Diabetes	32
Dementia	39
Cancer	13

Medicare Procedure and Patient Information

2022 Medicare Procedure Volume

The top procedures that Dr. Diane S. Book, MD treated as a neurologist in Milwaukee, WI during 2022 were hospital care and inpatient care.

Volume of procedures performed by Dr. Diane S. Book, MD for Medicare patients.

doctor visit	152
hospital care	193
inpatient care	193

2022 Medicare Patient Data

Information about Medicare patients treated by Dr. Diane S. Book, MD.

**Gender**
Male	102
Female	123

**Ethnicity**
Non-Hispanic White	174
Black	23
Hispanic	0
Asian	0
Other	15
Native American	0

**Age**
From 65 to 74	91
From 75 to 84	69
85 and over	44
Less than 65	21

Conditions of Medicare patients treated by Dr. Diane S. Book, MD in 2022

Hypertension	75
High Cholesterol	75
Stroke	57
Ischemic Heart Disease	32
Depression	32
Chronic Kidney Disease	35
Asthma	12
Osteoperosis	13
Atrial Fibrilation	25
Heart Failure	22
Chronic Obstructive Pulmonary Disease	19
Diabetes	32
Dementia	32
Cancer	19

Medicare Procedure and Patient Information

Average Medicare Procedure Volume From 2012 - 2022

Volume of procedures performed by Dr. Diane S. Book, MD for Medicare patients.

The highest averages for the top procedures that Dr. Diane S. Book, MD treated as a neurologist in Milwaukee, WI were hospital care, inpatient care and outpatient care.

doctor visit	203
hospital care	184
inpatient care	183
outpatient care	11

Average Medicare Patient Data From 2012 - 2022

Information about Medicare patients treated by Dr. Diane S. Book, MD.

**Gender**
Male	123
Female	159

**Ethnicity**
Black / African American	36
Asian / Pacific Islander	0
Non-Hispanic White	223
Native American / Alaskan Native	0
Hispanic	0
Other	2

**Age**
75 to 84	94
85 and over	49
Less than 65	41
65 to 74	98

Average of Total of Conditions of Medicare patients treated by Dr. Diane S. Book, MD From 2012 - 2022

The highest averages of the most common conditions of Medicare patients that Dr. Diane S. Book, MD treated were hypertension, high cholesterol, stroke and dementia.

Hypertension	67
High Cholesterol	58
Stroke	43
Ischemic Heart Disease	35
Depression	32
Chronic Kidney Disease	34
Asthma	9
Osteoporosis	10
Heart Failure	22
Chronic Obstructive Pulmonary Disease	12
Diabetes	27
Atrial Fibrillation	16
Dementia	40
Cancer	11

Education & Training

Dr. Diane S. Book, MD graduated from Medical College of Wisconsin in 1991. She completed residency at Medical College of Wisconsin Affiliated Hospitals. She is certified by the Neurology and has a state license in Wisconsin.

Medical School: Medical College of Wisconsin (1991)

Residency: Medical College of Wisconsin Affiliated Hospitals (1995)

Board Certification: Neurology

Licensed In: Wisconsin

Affiliations & Hospitals

Dr. Diane S. Book, MD is associated with these hospitals and organizations:

Medical College of Wisconsin

Froedtert Hospital

Froedtert & the Medical College of Wisconsin Regional Health Network

Froedtert Hospital - Milwaukee

Ratings & Reviews

Dr. Diane S. Book, MD has an exceptional overall rating with an average of 4.85 out of 5 stars based on 59 ratings. We collect ratings and reviews of Dr. Diane S. Book, MD from all over the web to help you find the right in Milwaukee, WI.

4.85

Overall Rating

(59 Ratings)

Leave a Review

Reviews From Around The Web

Overall Rating: 5.0 2024-07-29

Patient verified via Press Ganey

She was so wonderful with my husband, who has dementia that she is worth however long you need to, to get an appointment.

Overall Rating: 5.0 2025-04-13

Patient verified via Press Ganey

Thank you for your support, guidance and focus to help me manage my health.

Overall Rating: 5.0 2024-07-15

Patient verified via Press Ganey

Dr Book was very kind and explained things well. I didn't feel rushed.

Overall Rating: 5.0 2025-06-25

Patient verified via Press Ganey

Dr. Book was very helpful and kind in explaining my treatment.

Overall Rating: 5.0 2023-11-16

Patient verified via Press Ganey

Dr. Book is exceptional. I was so satisfied with my care.

General Payments

These charts describe general payments received by Dr. Diane S. Book, MD. Doctors may receive payments for a number of reasons, including meal compensation, travel compensation, and consulting.

**Payments by Company**
E.R. Squibb & Sons, L.L.C.	$120 ELIQUIS $120
Microtransponder, Inc.	$109 $109

**Types of Payments**
Food and Beverage	$229

Biography

Dr. Diane Book is a specialist in neurology (brain & spinal cord disease) in Milwaukee, WI. Dr. Book's average patient rating is 5.0 stars (out of 5). These areas are among her clinical interests: transient ischemic attack (TIA), aphasia, and ischemic stroke. Her hospital/clinic affiliations include Froedtert Hospital and Medical College of Wisconsin. According to Doctor.com, she is currently accepting new patients at her office in Milwaukee, WI. She attended Medical College of Wisconsin for medical school and subsequently trained at a hospital affiliated with Medical College of Wisconsin for residency.