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Dr. William E. Karnes JR., MD

Accepting New Patients

(William E. Karnes, MD)

(61 Ratings)

Specializes in: Gastroenterology (Digestive System), General Practice and Adult Gastroenterology

University of Minnesota Medical School (1982)

Professional interests include: colorectal cancer screening, capsule endoscopy, gastrointestinal bleeding, and more.

101 The City Drive South Building 22C
Orange, CA 92868

(949) 824-8600

Dr. William E. Karnes JR., MD is a gastroenterologist in Orange, CA specializing in gastroenterology (digestive system), general practice and adult gastroenterology. He graduated from University of Minnesota Medical School in 1982 and has 44 years of experience. Dr. William E. Karnes JR., MD is affiliated with UCI Health, UCI Health Chao Family Comprehensive Digestive Disease Center and UC REGENTS.

Office Locations

101 The City Drive South Building 22C
Orange, CA 92868

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1640 Newport Boulevard Suite 350
Costa Mesa, CA 92627

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1 Medical Plaza Drive
Irvine, CA 92697

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1640 Newport Boulevard Suite 100
Costa Mesa, CA 92627

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In The News (see more mentions in the news)

“The rise in young-onset colorectal cancer correlates with a doubling of the prevalence of childhood obesity over the last 30 years, now affecting 20% of those under age 20," Dr. William Karnes,...”—"Colorectal cancer is rising among younger adults and scientists are racing to uncover why", CBS News, March 2023

“"Colon cancer is the second-leading cause of cancer in the United States," UC-Irvine Health Dr. William Karnes said.”—"HealthWatch: Artificial Intelligence Used To Detect, Prevent Colon Cancer", CBS News, October 2018

“Using a convolutional neural network (CNN) model -- a type of deep learning that is especially effective at performing image classification -- researchers obtained an accuracy of 96% and AUC (area...”—"Deep Learning May Help Detect Colon Polyps", MedPage Today, October 2017

Noteworthy Medicare Patient Procedures Performed by Dr. William E. Karnes JR., MD in 2023

Click on any procedure below to see further details on volume and pricing among Medicare patients.

Top 5%

By Volume:

colonoscopy

endoscopy

wireless esophageal pH monitoring

By Affordability:

diagnostic EGD without biopsy

wireless esophageal pH monitoring

In 2023, among providers in related specialties within California, Dr. William E. Karnes JR., MD performed more colonoscopy, endoscopy, and wireless esophageal pH monitoring (Bravo test) procedures for Medicare patients than 95% of them and he also had a list price for diagnostic EGD without biopsy, and wireless esophageal pH monitoring (Bravo test) that was lower than the list prices billed to Medicare by 95% of them. Actual amounts paid by patients can vary widely depending on a number of factors, including insurance coverage. A lower list price, however, might mean lower fees when paying without insurance.

Top 10%

By Volume:

colonoscopy with biopsy

colonoscopy with lesion removal

EGD with biopsy

gastrointestinal biopsy

gastrointestinal procedures

removal of lesion

screening colonoscopy

In 2023, Dr. William E. Karnes JR., MD performed more colonoscopy with biopsy, colonoscopy with lesion removal, EGD with biopsy, gastrointestinal biopsy, gastrointestinal procedures, removal of lesion (e.g. growth), and screening colonoscopy procedures for Medicare patients than 90% of providers in related specialties within California.

Top 25%

By Volume:

EGD with lesion removal

preventive care

By Affordability:

capsule endoscopy

diagnostic EGD

diagnostic upper endoscopy

EGD with biopsy

EGD with lesion removal

esophagogastroduodenoscopy

therapeutic EGD

therapeutic upper endoscopy

upper endoscopy

upper endoscopy with biopsy

upper endoscopy with lesion removal

In 2012, among providers in related specialties within California, Dr. William E. Karnes JR., MD performed more EGD with lesion removal, and preventive care procedures for Medicare patients than 75% of them and he also had a list price for capsule endoscopy, diagnostic EGD, diagnostic upper endoscopy, EGD with biopsy, EGD with lesion removal, esophagogastroduodenoscopy (EGD), therapeutic EGD, therapeutic upper endoscopy, upper endoscopy, upper endoscopy with biopsy, and upper endoscopy with lesion removal that was lower than the list prices billed to Medicare by 75% of them. Actual amounts paid by patients can vary widely depending on a number of factors, including insurance coverage. A lower list price, however, might mean lower fees when paying without insurance.

Medicare Procedure and Patient Information

2012 Medicare Procedure Volume

The top procedures that Dr. William E. Karnes JR., MD treated as a gastroenterologist in Orange, CA during 2012 were minimally invasive procedures, gastrointestinal procedures, removal of lesion (e.g. growth) and diagnostic procedures.

Volume of procedures performed by Dr. William E. Karnes JR., MD for Medicare patients.

diagnostic procedures	241
doctor visit	240
gastrointestinal procedures	276
hospital care	108
inpatient care	108
minimally invasive procedures	309
preventive care	19
removal of lesion (e.g. growth)	241

Medicare Procedure and Patient Information

2013 Medicare Procedure Volume

The top procedures that Dr. William E. Karnes JR., MD treated as a gastroenterologist in Orange, CA during 2013 were minimally invasive procedures, gastrointestinal procedures, removal of lesion (e.g. growth) and diagnostic procedures.

Volume of procedures performed by Dr. William E. Karnes JR., MD for Medicare patients.

diagnostic procedures	268
doctor visit	294
gastrointestinal procedures	364
hospital care	63
injections	12
inpatient care	63
minimally invasive procedures	406
preventive care	55
removal of lesion (e.g. growth)	268

2013 Medicare Patient Data

Information about Medicare patients treated by Dr. William E. Karnes JR., MD.

**Gender**
Male	189
Female	219

**Ethnicity**
Non-Hispanic White	214
Black	0
Hispanic	103
Asian	68
Other	0
Native American	0

**Age**
From 65 to 74	183
From 75 to 84	112
85 and over	32
Less than 65	81

Conditions of Medicare patients treated by Dr. William E. Karnes JR., MD in 2013

Hypertension	72
High Cholesterol	52
Stroke	8
Ischemic Heart Disease	36
Depression	26
Chronic Kidney Disease	33
Asthma	8
Osteoperosis	15
Atrial Fibrilation	13
Heart Failure	21
Chronic Obstructive Pulmonary Disease	13
Diabetes	39
Dementia	10
Cancer	17

Medicare Procedure and Patient Information

2014 Medicare Procedure Volume

The top procedures that Dr. William E. Karnes JR., MD treated as a gastroenterologist in Orange, CA during 2014 were minimally invasive procedures, gastrointestinal procedures, removal of lesion (e.g. growth) and diagnostic procedures.

Volume of procedures performed by Dr. William E. Karnes JR., MD for Medicare patients.

diagnostic procedures	267
doctor visit	362
gastrointestinal procedures	348
hospital care	14
inpatient care	14
minimally invasive procedures	385
preventive care	50
removal of lesion (e.g. growth)	267

2014 Medicare Patient Data

Information about Medicare patients treated by Dr. William E. Karnes JR., MD.

**Gender**
Male	184
Female	233

**Ethnicity**
Non-Hispanic White	236
Black	0
Hispanic	93
Asian	67
Other	0
Native American	0

**Age**
From 65 to 74	183
From 75 to 84	118
85 and over	33
Less than 65	83

Conditions of Medicare patients treated by Dr. William E. Karnes JR., MD in 2014

Hypertension	68
High Cholesterol	57
Stroke	7
Ischemic Heart Disease	35
Depression	32
Chronic Kidney Disease	29
Asthma	7
Osteoperosis	16
Atrial Fibrilation	12
Heart Failure	21
Chronic Obstructive Pulmonary Disease	13
Diabetes	35
Dementia	12
Cancer	15

Medicare Procedure and Patient Information

2015 Medicare Procedure Volume

The top procedures that Dr. William E. Karnes JR., MD treated as a gastroenterologist in Orange, CA during 2015 were minimally invasive procedures, gastrointestinal procedures, removal of lesion (e.g. growth) and diagnostic procedures.

Volume of procedures performed by Dr. William E. Karnes JR., MD for Medicare patients.

diagnostic procedures	284
doctor visit	341
gastrointestinal procedures	303
hospital care	30
inpatient care	30
minimally invasive procedures	343
removal of lesion (e.g. growth)	284

2015 Medicare Patient Data

Information about Medicare patients treated by Dr. William E. Karnes JR., MD.

**Gender**
Male	362
Female	440

**Ethnicity**
Non-Hispanic White	438
Black	28
Hispanic	192
Asian	118
Other	0
Native American	0

**Age**
From 65 to 74	366
From 75 to 84	202
85 and over	58
Less than 65	176

Conditions of Medicare patients treated by Dr. William E. Karnes JR., MD in 2015

Hypertension	71
High Cholesterol	61
Stroke	9
Ischemic Heart Disease	34
Depression	31
Chronic Kidney Disease	33
Asthma	14
Osteoperosis	15
Atrial Fibrilation	11
Heart Failure	22
Chronic Obstructive Pulmonary Disease	16
Diabetes	40
Dementia	11
Cancer	17

Medicare Procedure and Patient Information

2016 Medicare Procedure Volume

The top procedures that Dr. William E. Karnes JR., MD treated as a gastroenterologist in Orange, CA during 2016 were minimally invasive procedures, gastrointestinal procedures, removal of lesion (e.g. growth) and diagnostic procedures.

Volume of procedures performed by Dr. William E. Karnes JR., MD for Medicare patients.

diagnostic procedures	296
doctor visit	348
gastrointestinal procedures	320
minimally invasive procedures	364
preventive care	12
removal of lesion (e.g. growth)	296

2016 Medicare Patient Data

Information about Medicare patients treated by Dr. William E. Karnes JR., MD.

**Gender**
Male	177
Female	235

**Ethnicity**
Non-Hispanic White	246
Black	0
Hispanic	72
Asian	77
Other	0
Native American	0

**Age**
From 65 to 74	207
From 75 to 84	105
85 and over	32
Less than 65	68

Conditions of Medicare patients treated by Dr. William E. Karnes JR., MD in 2016

Hypertension	71
High Cholesterol	58
Stroke	5
Ischemic Heart Disease	33
Depression	24
Chronic Kidney Disease	33
Asthma	18
Osteoperosis	13
Atrial Fibrilation	11
Heart Failure	19
Chronic Obstructive Pulmonary Disease	13
Diabetes	37
Dementia	9
Cancer	15

Medicare Procedure and Patient Information

2017 Medicare Procedure Volume

The top procedures that Dr. William E. Karnes JR., MD treated as a gastroenterologist in Orange, CA during 2017 were minimally invasive procedures, gastrointestinal procedures, removal of lesion (e.g. growth) and diagnostic procedures.

Volume of procedures performed by Dr. William E. Karnes JR., MD for Medicare patients.

diagnostic procedures	283
doctor visit	316
gastrointestinal procedures	317
hospital care	14
inpatient care	14
minimally invasive procedures	350
preventive care	16
removal of lesion (e.g. growth)	283

2017 Medicare Patient Data

Information about Medicare patients treated by Dr. William E. Karnes JR., MD.

**Gender**
Male	186
Female	235

**Ethnicity**
Non-Hispanic White	265
Black	0
Hispanic	67
Asian	70
Other	0
Native American	0

**Age**
From 65 to 74	204
From 75 to 84	113
85 and over	33
Less than 65	71

Conditions of Medicare patients treated by Dr. William E. Karnes JR., MD in 2017

Hypertension	67
High Cholesterol	53
Stroke	6
Ischemic Heart Disease	31
Depression	29
Chronic Kidney Disease	32
Asthma	10
Osteoperosis	16
Atrial Fibrilation	16
Heart Failure	19
Chronic Obstructive Pulmonary Disease	13
Diabetes	31
Dementia	10
Cancer	15

Medicare Procedure and Patient Information

2018 Medicare Procedure Volume

The top procedures that Dr. William E. Karnes JR., MD treated as a gastroenterologist in Orange, CA during 2018 were minimally invasive procedures, gastrointestinal procedures, removal of lesion (e.g. growth) and diagnostic procedures.

Volume of procedures performed by Dr. William E. Karnes JR., MD for Medicare patients.

diagnostic procedures	309
doctor visit	335
gastrointestinal procedures	407
minimally invasive procedures	415
preventive care	42
removal of lesion (e.g. growth)	309

2018 Medicare Patient Data

Information about Medicare patients treated by Dr. William E. Karnes JR., MD.

**Gender**
Male	191
Female	256

**Ethnicity**
Non-Hispanic White	253
Black	0
Hispanic	67
Asian	95
Other	18
Native American	0

**Age**
From 65 to 74	209
From 75 to 84	130
85 and over	32
Less than 65	76

Conditions of Medicare patients treated by Dr. William E. Karnes JR., MD in 2018

Hypertension	62
High Cholesterol	57
Stroke	5
Ischemic Heart Disease	34
Depression	28
Chronic Kidney Disease	30
Asthma	9
Osteoperosis	15
Atrial Fibrilation	12
Heart Failure	17
Chronic Obstructive Pulmonary Disease	11
Diabetes	31
Dementia	10
Cancer	20

Medicare Procedure and Patient Information

2019 Medicare Procedure Volume

The top procedures that Dr. William E. Karnes JR., MD treated as a gastroenterologist in Orange, CA during 2019 were minimally invasive procedures, gastrointestinal procedures, removal of lesion (e.g. growth) and diagnostic procedures.

Volume of procedures performed by Dr. William E. Karnes JR., MD for Medicare patients.

diagnostic procedures	321
doctor visit	388
gastrointestinal procedures	407
hospital care	13
inpatient care	13
minimally invasive procedures	433
preventive care	45
removal of lesion (e.g. growth)	321

2019 Medicare Patient Data

Information about Medicare patients treated by Dr. William E. Karnes JR., MD.

**Gender**
Male	230
Female	283

**Ethnicity**
Non-Hispanic White	315
Black	16
Hispanic	68
Asian	98
Other	0
Native American	0

**Age**
From 65 to 74	225
From 75 to 84	158
85 and over	40
Less than 65	90

Conditions of Medicare patients treated by Dr. William E. Karnes JR., MD in 2019

Hypertension	66
High Cholesterol	60
Stroke	6
Ischemic Heart Disease	36
Depression	30
Chronic Kidney Disease	35
Asthma	10
Osteoperosis	18
Atrial Fibrilation	14
Heart Failure	20
Chronic Obstructive Pulmonary Disease	11
Diabetes	32
Dementia	10
Cancer	21

Medicare Procedure and Patient Information

2020 Medicare Procedure Volume

The top procedures that Dr. William E. Karnes JR., MD treated as a gastroenterologist in Orange, CA during 2020 were minimally invasive procedures, gastrointestinal procedures, removal of lesion (e.g. growth) and diagnostic procedures.

Volume of procedures performed by Dr. William E. Karnes JR., MD for Medicare patients.

diagnostic procedures	324
doctor visit	346
gastrointestinal procedures	417
minimally invasive procedures	440
preventive care	49
removal of lesion (e.g. growth)	324

2020 Medicare Patient Data

Information about Medicare patients treated by Dr. William E. Karnes JR., MD.

**Gender**
Male	214
Female	261

**Ethnicity**
Non-Hispanic White	288
Black	12
Hispanic	65
Asian	90
Other	20
Native American	0

**Age**
From 65 to 74	230
From 75 to 84	139
85 and over	34
Less than 65	72

Conditions of Medicare patients treated by Dr. William E. Karnes JR., MD in 2020

Hypertension	65
High Cholesterol	60
Stroke	5
Ischemic Heart Disease	41
Depression	28
Chronic Kidney Disease	37
Asthma	9
Osteoperosis	19
Atrial Fibrilation	12
Heart Failure	19
Chronic Obstructive Pulmonary Disease	13
Diabetes	30
Dementia	14
Cancer	19

Medicare Procedure and Patient Information

2021 Medicare Procedure Volume

The top procedures that Dr. William E. Karnes JR., MD treated as a gastroenterologist in Orange, CA during 2021 were minimally invasive procedures, gastrointestinal procedures, removal of lesion (e.g. growth) and diagnostic procedures.

Volume of procedures performed by Dr. William E. Karnes JR., MD for Medicare patients.

balloon dilation	13
diagnostic procedures	316
doctor visit	427
esophageal dilation	13
gastrointestinal procedures	450
minimally invasive procedures	484
preventive care	71
removal of lesion (e.g. growth)	316

2021 Medicare Patient Data

Information about Medicare patients treated by Dr. William E. Karnes JR., MD.

**Gender**
Male	252
Female	301

**Ethnicity**
Non-Hispanic White	343
Black	0
Hispanic	77
Asian	98
Other	0
Native American	0

**Age**
From 65 to 74	261
From 75 to 84	166
85 and over	49
Less than 65	77

Conditions of Medicare patients treated by Dr. William E. Karnes JR., MD in 2021

Hypertension	64
High Cholesterol	65
Stroke	7
Ischemic Heart Disease	41
Depression	29
Chronic Kidney Disease	35
Asthma	10
Osteoperosis	22
Atrial Fibrilation	9
Heart Failure	18
Chronic Obstructive Pulmonary Disease	12
Diabetes	30
Dementia	11
Cancer	16

Medicare Procedure and Patient Information

2022 Medicare Procedure Volume

The top procedures that Dr. William E. Karnes JR., MD treated as a gastroenterologist in Orange, CA during 2022 were minimally invasive procedures, gastrointestinal procedures, removal of lesion (e.g. growth) and diagnostic procedures.

Volume of procedures performed by Dr. William E. Karnes JR., MD for Medicare patients.

diagnostic procedures	381
doctor visit	400
gastrointestinal procedures	558
minimally invasive procedures	586
preventive care	84
removal of lesion (e.g. growth)	381

2022 Medicare Patient Data

Information about Medicare patients treated by Dr. William E. Karnes JR., MD.

**Gender**
Male	304
Female	393

**Ethnicity**
Non-Hispanic White	410
Black	0
Hispanic	99
Asian	144
Other	25
Native American	0

**Age**
From 65 to 74	340
From 75 to 84	205
85 and over	48
Less than 65	104

Conditions of Medicare patients treated by Dr. William E. Karnes JR., MD in 2022

Hypertension	68
High Cholesterol	75
Stroke	11
Ischemic Heart Disease	27
Depression	28
Chronic Kidney Disease	22
Asthma	15
Osteoperosis	26
Atrial Fibrilation	15
Heart Failure	14
Chronic Obstructive Pulmonary Disease	15
Diabetes	30
Dementia	6
Cancer	25

Medicare Procedure and Patient Information

Average Medicare Procedure Volume From 2012 - 2022

Volume of procedures performed by Dr. William E. Karnes JR., MD for Medicare patients.

The highest averages for the top procedures that Dr. William E. Karnes JR., MD treated as a gastroenterologist in Orange, CA were minimally invasive procedures, gastrointestinal procedures, removal of lesion (e.g. growth) and diagnostic procedures.

balloon dilation	13
diagnostic procedures	299
doctor visit	345
esophageal dilation	13
gastrointestinal procedures	378
hospital care	40
injections	12
inpatient care	40
minimally invasive procedures	410
preventive care	44
removal of lesion (e.g. growth)	299

Average Medicare Patient Data From 2012 - 2022

Information about Medicare patients treated by Dr. William E. Karnes JR., MD.

**Gender**
Male	208
Female	259

**Ethnicity**
Black / African American	5
Asian / Pacific Islander	84
Non-Hispanic White	273
Hispanic	82
Native American / Alaskan Native	0
Other	5

**Age**
75 to 84	131
85 and over	35
Less than 65	81
65 to 74	218

Average of Total of Conditions of Medicare patients treated by Dr. William E. Karnes JR., MD From 2012 - 2022

The highest averages of the most common conditions of Medicare patients that Dr. William E. Karnes JR., MD treated were hypertension, high cholesterol, ischemic heart disease and diabetes.

Hypertension	61
High Cholesterol	54
Stroke	6
Ischemic Heart Disease	31
Depression	25
Chronic Kidney Disease	29
Asthma	10
Osteoporosis	15
Heart Failure	17
Chronic Obstructive Pulmonary Disease	11
Diabetes	30
Atrial Fibrillation	11
Cancer	16
Dementia	9

Education & Training

Dr. William E. Karnes JR., MD graduated from University of Minnesota Medical School in 1982. He completed residency at University of Minnesota Affiliated Hospitals. He is certified by the American Board of Internal Medicine - Gastroenterology American Board of Internal Medicine - Internal Medicine and has a state license in California.

Medical School: University of Minnesota Medical School (1982)

Residency: University of Minnesota Affiliated Hospitals

Board Certification: American Board of Internal Medicine - Gastroenterology American Board of Internal Medicine - Internal Medicine

Licensed In: California

Affiliations & Hospitals

Dr. William E. Karnes JR., MD is associated with these hospitals and organizations:

UCI Health

UCI Health Chao Family Comprehensive Digestive Disease Center

UC REGENTS

Ratings & Reviews

Dr. William E. Karnes JR., MD has an exceptional overall rating with an average of 4.8 out of 5 stars based on 61 ratings. We collect ratings and reviews of Dr. William E. Karnes JR., MD from all over the web to help you find the right in Orange, CA.

4.8

Overall Rating

(61 Ratings)

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General Payments

These charts describe general payments received by Dr. William E. Karnes JR., MD. Doctors may receive payments for a number of reasons, including meal compensation, travel compensation, and consulting.

**Payments by Company**
Medivators Inc.	$30,203 AMPLIFEYE ENDOSCOPIC DEVICE $18,682	Endocuff $339	JET PREP $75	$11,107
Cook Medical LLC	$696 Cook Medical Hemostasis $251	Hemospray $156	EchoTip $155	Cook Medical Biliary $134
Janssen Scientific Affairs, LLC	$306 REMICADE $306
Wilson Cook Medical Incorporated	$299 Cook Medical Endoscopic Ultrasound $169	Cook Medical Biliary $130
Gilead Sciences Inc	$219 Epclusa $118	Harvoni $101
Other	$1,029 GATTEX $125	LINX $124	Ocaliva $123	Non-Covered-Product $120	Cook Medical Biliary $114	Other $423

**Types of Payments**
Consulting Fee	$26,526
Food and Beverage	$3,333
Travel and Lodging	$2,894

Biography

Dr. William Karnes is a specialist in general practice and adult gastroenterology in Orange, CA, Irvine, CA, and Costa Mesa, CA. He is especially interested in gastrointestinal bleeding, colorectal problems, and colorectal cancer screening. Dr. Karnes is professionally affiliated with UCI Health. He attended the University of Minnesota Medical School and subsequently trained at a hospital affiliated with the University of Minnesota for residency. Dr. Karnes is rated highly by his patients. Distinctions awarded to Dr. Karnes include: Southern California Super Doctors; Physicians of Excellence, Orange County Medical Association; and Best Doctors in America - Gastroenterology. He has an open panel in Orange, CA according to Yext.